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An unvaccinated angry pandemic with the spread of Delta. Case up in all 50 states

Expansion / The Anthony Church says goodbye through a glass window to a daughter recovering from COVID-19 at the ICU of Johnston Memorial Hospital in Abingdon, Virginia, on June 16, 2021.

Due to the rapid increase in highly contagious delta mutants and the significant stagnation of national vaccination efforts, the COVID-19 pandemic is rampant among unvaccinated people in the United States.

Cases of COVID-19 are increasing in all 50 states and the District of Columbia. Currently, the states with the highest average daily new cases per 100,000 are Arkansas, Missouri, Florida, Louisiana, and Nevada, all with below-average immunization rates. Nationally, the average number of cases per day has increased by 140% in the last two weeks. Hospitalization and death are weeks behind the increase in case numbers, increasing by 34% and 33%, respectively.

Compared to other pandemics, the number of cases, hospitalizations and deaths nationwide is low, equal to or below the number seen in April 2020. Unvaccinated case rate In some places, it’s comparable to what you see in the heyday of a pandemic. In addition, the number is increasing rapidly in areas where the scope of vaccination is narrow.

In Missouri, where only 40% of the population is fully vaccinated, new daily case rates are seen at the foot of the winter peak, as high as last October. And some of the state’s hotspots have set records. For example, in the southwestern county of Tanny, the 7-day average of new daily cases is higher than at any previous time point, with an average of 55 new cases per day. The previous highest average was 45 new cases per day, and the county hit again on 22nd November and 10th December. Across the Arkansas border, Baxter County set a record of 42 new cases last week, the highest average of new cases daily. Case per day. This surpassed the previous record of 32 set in early January. Only 33 percent of Baxter County’s population is fully vaccinated.

The surge in these cases has led to an increase in hospitalizations. In Baxter, hospitalizations have increased by 340% in the last two weeks. In southwestern Missouri The hospital is overwhelmed, Intensive care unit has reached capacity, ventilator shortage, hospital reports shortage of nurses.Last week, Missouri’s Springfield-Greene County Health Department Requested state funding Establish a field hospital to address the surge in patients with severe COVID-19 cases.

Vulnerability

In these places and elsewhere in the country, the majority of people hospitalized with COVID-19 are not vaccinated. At the White House press conference last FridayRochelle Walensky, director of the Centers for Disease Control and Prevention, reiterated that more than 97 percent of COVID-19 patients entering hospitals across the country were unvaccinated.

In addition to low vaccination rates, the epidemic of delta coronavirus mutants is behind a dark surge. Delta is estimated to be more than twice as infectious as the original pandemic coronavirus strain. It has been the most predominant subspecies in the world since it was first detected in India in December 2020. And since it was first detected in the United States in March Dominant stock here, Immediately overtake Alpha (B.1.1.7). Just as many in the United States have begun to relax their vigilance and ease the use of masks and physical distances, it is the fact that it has arrived that is helping the spread of epidemic variants. is.

Fully vaccinated people are primarily protected from the Delta. Current vaccines are still very effective against the development of COVID-19 from Delta and other variant of concern. A small number of people can develop so-called “breakthrough infections,” but those infections are almost asymptomatic or mild. However, unvaccinated people are completely vulnerable. In addition, those who have been vaccinated only once, or who have only recovered from COVID-19, are not in much better condition than those who are not completely vaccinated.

To A study published in Nature earlier this month, Researchers tested the immune response of people who recovered from COVID-19 early in the pandemic before the onset of the delta. Specifically, the researchers focused on the participants’ neutralizing antibodies. This is the most potent type of antibody that is believed to be important in defense against the pandemic coronavirus. Looking at people who recovered from early cases of COVID-19, researchers found that neutralizing antibodies were 4-6 times less effective in fighting delta mutants than fighting previous versions of the virus. did. Similarly, those who received only one mRNA vaccine had few detectable neutralizing antibodies that acted against deltas.

However, when recovered people received a single vaccination, or partially vaccinated people received a second vaccination, neutralizing antibodies soared and both groups were highly protected. Was considered to be.

Vaccination outlook

This finding has spurred health professionals to increase their demand for vaccination. This is clearly effective against deltas if done in time. The delta spreads rapidly and can take up to 6 weeks to be fully vaccinated and protected. For unvaccinated people, it is important to take a shot as soon as possible to avoid catching and spreading the delta.

But according to New polling data from CBS News, It seems unlikely that there will be a new wave of vaccination. Only 48 percent of unvaccinated and partially vaccinated people said they were concerned about Delta. Among fully vaccinated people, 72 percent reported concern about varieties.

Despite the fact that current COVID-19 vaccines have proven to be very effective and safe, 53% of unvaccinated or partially vaccinated people are concerned about side effects. Said in a poll. Fifty percent of the group cited lack of trust in the government as a reason for not being vaccinated. And 45 percent said they didn’t trust science. All of these percentages are higher than in previous polls, indicating that sentiment towards these vaccines is consolidating among unvaccinated individuals.

Some unvaccinated people who may be more convincing Waiting for the vaccine to be fully approved From the Food and Drug Administration (currently they are licensed by the FDA under an Emergency Use Authorization).On Friday, Pfizer and BioNTech said the FDA had allowed them. Priority examination designation Because of their mRNA vaccine, but they did not expect a full approval decision until January 2022.

Currently, vaccine providers receive only about 520,000 COVID-19 vaccines per day, down from the April daily record of 4.6 million. More than 161 million people have been vaccinated 48.6 percent of the U.S. population is fully vaccinated..

https://arstechnica.com/?p=1781469 An unvaccinated angry pandemic with the spread of Delta. Case up in all 50 states

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